Trehalose, Lyophilization Certified, 500 gm

D-Trehalose, Lyophilization Certified, is a lyoprotectant, which effectively maintains the conformation of proteins and other biomolecules as water is removed during the freeze-drying process.  This non-reducing disaccharide (two glucose molecules linked by the anomeric carbon), provides the same type of protection during lyophilization that sucrose does, though D-Trehalose is less likely to cause sample collapse.  D-Trehalose is a crystalline dihydrate powder with a molecular weight of 378.33 g/mol.  It is soluble in water to 6.8” at 20° C.  It is an effective lyoprotectant of proteins at a weight/volume concentration of 1%-2%.

Each lot of our D-Trehalose is tested to ensure that it is effective at preserving protein structure and activity.  D-Trehalose is available with a Certificate of Analysis, attesting to the absence of proteases and nucleases and its ability to form a solid cake/matrix that can easily be rehydrated.

Important Notice Regarding Use

This product is not approved or intended for use on or in humans. Although the product is not considered hazardous to human health, our organization is not certified or licensed to manufacture, handle, or distribute materials for human-related applications. Accordingly, this product must not be used in any medical, clinical, or human-contact context.

Freeze Drying Product Line Sales Sheet(pdf)

Trehalose SDS(pdf)